Drugs and blood products for treatment of and prophlyaxis against COVID-19

COVID-19 living network meta-analysis

WHAT THE DATA SHOWS

DRUG TREATMENTS FOR COVID-19

Corticosteriods probably reduce mortality and mechanical ventilation in patients with covid-19 compared with standard care.

Azithromycin, hydroxychloroquine, lopinavir/ritonavir, interferon-beta, and tocilizumab may not reduce risk of death or have an effect on any other patient-important outcome.

The impact of remdesivir on mortality, mechanical ventilation, length of hospital stay, and duration of symptoms is uncertain, but it probably does not substantially increase adverse effects leading to drug discontinuation.

*Mortality data includes trials up to 14 December, 2020.

Evidence for all other outcomes includes trials identified up to 21 October 2020.

© 2020 by COVID-19 Living Network Meta-Analysis